SUPER DONOR FECAL TRANSPLANT HELPS IBS
SUPER DONOR FECAL TRANSPLANT HELPS IBS
Check out this article in Healio about a study that supports a stool transplant from a “super donor” that effectively helps to treat IRRITABLE BOWEL SYNDROME!
Helio Gastroenterology: ‘Super donor’ FMT effective in IBS
“Fecal microbiota transplantation [taking stool from one person and putting it into another person’s colon] is an effective treatment for patients with irritable bowel syndrome, but the fecal sample must come from a “super donor,” according to study results presented at United European Gastroenterology Week.”
“Microbiota dysbiosis is thought to play an important role in the pathophysiology of IBS,” Magdy El-Salhy, MD, PhD, professor of gastroenterology and hepatology at Bergen University in Norway, said in a press release. “However, previous studies investigating FMT in this condition have produced conflicting results.”
“El-Salhy tested the efficacy of FMT for IBS using stool samples from a single “super donor,” a Caucasian man aged 36 years. The donor was healthy, had a normal BMI, exercised regularly, was born via vaginal birth and was breast fed. He was not taking any medications, only received three courses of antibiotics in his lifetime and regularly took dietary supplements.”
“Researchers randomly assigned 164 patients with IBS to receive either 30 grams or 60 grams of FMT or placebo. The primary outcome of the study was a reduction in IBS symptoms, defined as a decrease in the IBS-Severity Scoring System (IBS-SSS) total of at least 50 points 3 months after FMT. Secondary endpoints included reduction in dysbiosis index as measured by the GA-map Dysbiosis Test (Genetic Analysis AS).
Researchers found that more patients in the 30-gram (75.9%) and 60-gram (87.3%) FMT groups achieved response compared with placebo (23.6%). Patients who received FMT also experienced improvements in fatigue and quality of life.
Additionally, 35.2% of patients in the 30-gram group and 47.3% in the 60-gram group achieved symptom remission — defined as IBS-SSS improvement of at least 175 points — compared with just 5.5% in the placebo group.”
These are impressive results, but they are not yet ready for prime time, so don’t go recruiting superhuman poop quite yet!
Our providers are well versed in all of the latest treatment options for IBS (and other functional GI conditions) including nutritional interventions, optimizing the mind-connection with gut directed hypnotherapy and cognitive behavioral therapy, and utilizing the huge variety of potentially beneficial supplements and medications. One size does not fit all – you need to have an individualized treatment plan. For now, wait for more evidence on fecal transplants – we will be ready when more evidence supports manipulation of the gut microbiome!
CONSULTATIONS WITH OUR DIETITIAN AND COUNSELOR ARE ROUTINELY COVERED BY STANDARD HEALTH INSURANCE – take advantage of the opportunity! TELEMEDICINE consultations are available now! We are eager to help IMPROVE YOUR QUALITY OF LIFE and have you THINK LESS ABOUT YOUR GUT. Call 224.407.4400 or visit compgihealth.com to schedule a consultation.